2017

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2017/№2

The main risk factors and features of coronary heart disease and acute myocardial infarction course in women

Bondareva Z. G.1, Fedorova E. L.1, Kungurtseva O. A.2, Tsygankova O. V.1, Ruyatkin D. S.1
1 – State Budgetary Educational Institution of Higher Professional Education, "Novosibirsk State Medical University" of the Ministry of Health of the Russian Federation, Krasnyj Prospekt 52, Novosibirsk 630091
2 – State Budgetary Institution of Health Care of the Novosibirsk Region, "Municipal Clinical Hospital of Emergency Medical Care #2", Yakusheva 41, Novosibirsk 630003

Keywords: coronary heart disease, women, risk factors, acute myocardial infarction, complications

DOI: 10.18087/rhj.2017.2.2325

Background. IHD is a leading cause for death in industrial countries, which accounts for 55% of cardiovascular fatalities in women and 43% in men. Available information in relevant literature is fragmented and inconsistent. Aim. To study major risk factors and characteristics of the clinical course of IHD and acute myocardial infarction (AMI) in women of different age. Materials and methods. 397 women aged 36 to 91 with documented AMI (ECG monitoring and measurement of troponin I or T levels) were evaluated. Arterial hypertension was detected in 76% of women younger than 55 and 87% of patients older than 55. Hypercholesterolemia (HCS) was observed in 56% of patients younger than 55 and in 74% of older women. A combination of HCS and hypertriglyceridemia highly correlated with overweight and abdominal obesity was observed in 87.2% of women older than 55 and 71% of women younger than 55. Impaired glucose tolerance and documented type 2 diabetes mellitus were found in 29.8% of patients older than 55 and only in 6.2% of women younger than 55. Disorders of the reproductive function were noted in 64% of patients younger than 55 and in 30% of patients older than 55. A «pre-infarction» period was observed in 21% of women of young and middle age and in 52% of patients older than 55 who had more severe AMI evident as development of fatal complications. Conclusion. Studying characteristics of IHD development and progression and earlier diagnosis will reduce the risk of fatal outcomes in women.
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Bondareva Z. G., Fedorova E. L., Kungurtseva O. A., Tsygankova O. V., Ruyatkin D. S. The main risk factors and features of coronary heart disease and acute myocardial infarction course in women. Russian Heart Journal. 2017;16 (2):110–115

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