2016


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2016/№3

Severe pulmonary hypertension in a long-living person with congenital heart disease

Tvorun O. P., Cherkashin D. V., Shakhnovich P. G., Zakharova A. I., Yalovets A. A.
Federal State Government Military Educational Institution of Higher Professional Education, “S. M. Kirov Military Medical Academy” of the RF Ministry of Defense, Akademika Lebedeva 6, St.-Petersburg 194044

Keywords: pulmonary hypertension, heart disease, ventricular septal defect, endothelin receptor antagonist, phosphodiesterase-5 inhibitors, prostacyclin analogue, IP receptor agonist, soluble guanylate cyclase stimulator

DOI: 10.18087/rhj.2016.3.2183

Based on clinical observation of a 92-year old patient, the authors addressed one of common cardiologic conditions, pulmonary hypertension. A peculiarity of the considered clinical case was detection of congenital heart disease, which served as a pathogenetic substrate for pulmonary hypertension at early stages of the disease with subsequent compensatory influence on systemic hemodynamics and formation of the right-to-left shunt, which allowed reducing pressure in the right heart and pulmonary circulation.
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Tvorun O. P., Cherkashin D. V., Shakhnovich P. G., Zakharova A. I., Yalovets A. A. Severe pulmonary hypertension in a long-living person with congenital heart disease. Russian Heart Journal. 2016;15 (3):217–220

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