2015


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2015/№6

Immediate and remote outcomes of surgical treatment for moderate ischemic mitral regurgitation in the TIME study

Chernyavsky A. M.1, Ruzmatov T. M.1, Efendiev V. U.1, Sakovich V. A.2, Podsosnikova T. N.1, Volokitina T. L.1, Batrynak A. A.3, Morozan V.3, Nesmachny A. S.1
1 – Federal State Budgetary Institution, “Academician E. N. Meshalkin Novosibirsk Research Institute of Circulatory Pathology” of the RF Ministry of Health Care, Rechkunovskaya 15, Novosibirsk 630055
2 – Federal State Budgetary Institution. “Federal Center of Cardiovascular Surgery” of the RF Ministry of Health Care, Karaulnaya 45, Krasnoyarsk 660020
3 – State Medical and Sanitary Institution, Ïstitute of Cardiology”, N. Testemitsan 29/1, Kishinev MD2025, Republic of Moldova

Keywords: ischemic mitral insufficiency, myocardial infarction, surgical methods of correction, coronary bypass surgery, coronary heart disease

DOI: 10.18087/rhj.2015.6.2106

Background. Treatment of moderate ischemic mitral regurgitation (IMR) is still a subject of debate. Aim. To compare immediate and remote outcomes of different surgical treatments for IHD complicated with moderate IMR. Materials and methods. Between May, 2011 through December, 2014, 120 patients underwent a surgery as a part of the multicenter, randomized study, Surgical Treatment of Ischemic Mitral rEgurgitation (TIME). 60 patients underwent isolated coronary bypass (CB) and 60 patients – CB with mitral valve annuloplasty (CB+MVA). The follow-up examination was performed at 12 months after the surgery. Results. Overall one-year post-surgery death rate was 6.7 % (4 patients) in the CB group and 8.3 % (5 patients) in the CB+MVA group (р=0.62). In one year after the surgery, the degree of mitral regurgitation showed a tendency to increase in the CB group and was either absent or mild in the combination treatment group. The HF NYHA functional class and scores of the quality of life questionnaire, SF-36, were comparable in both group at one year of surgery. Conclusion. In one year after the surgery, the combination surgery of CB with mitral valve plasty did not show any advantage. Obtaining more unbiased results will require a further study and data analysis at 3 and 5 years after the surgical treatment.
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Chernyavsky A. M., Ruzmatov T. M., Efendiev V. U., Sakovich V. A., Podsosnikova T. N., Volokitina T. L. et al. Immediate and remote outcomes of surgical treatment for moderate ischemic mitral regurgitation in the TIME study. Russian Heart Journal. 2015;14 (6):383–388

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