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Reduction of increased heart rate in arterial hypertension: clinical and predictive practicability

Kobalava Zh. D., Kiyakbaev G. K., Shavarov A. A.
Federal State Autonomous Educational Institution of Higher Education, "Russian University of Peoples' Friendship", Miklukho-Maklaya 6, Moscow 117198

Keywords: arterial hypertension, heart rate, arterial stiffness, beta-adrenergic blocker agents

DOI: 10.18087/rhj.2015.4.2102

Increased heart rate (HR) is an independent risk factor for all-cause mortality, sudden cardiac death, and cardiovascular (CV) death both in general population and individual subgroups. Data on the effect of pharmacologically slowed HR on prediction for patients with arterial hypertension (AH) who are characterized by tachycardia are far from being consistent. Results of some studies and meta-analyses have initiated debates on the place of β-blockers among hypotensive drugs in the aspect of reducing the risk for all-cause and cardiovascular mortality in this patient cohort. The review presents data that address the many-sided issue of clinical and practical significance of increased HR in AH.
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