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EchoCG data in ihd patients with different cardio-ankle vascular indexes

Sumin A. N., Osokina A. V., Shcheglova A. V., Verkoshanskaya E. M., Barbarash O. L.
Federal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases" at the Siberian Branch of the Russian Academy of Medical Sciences, Sosnovy Bulvar 6, Kemerovo 65000

Keywords: vascular stiffness, CAD, cardio-ankle vascular index, EchoCG

DOI: 10.18087/rhj.2015.3.1973

Background. Arterial stiffness is an integral index of the arterial wall condition. For this reason, this index has been extensively used in cardiological practice and considered one of RFs for cardiovascular diseases (CVD). Parameters of arterial stiffness have been reported to be related with impaired LV diastolic function. Aim. To evaluate parameters of systolic and diastolic heart function in IHD patients with different values of the cardio-ankle vascular index (CAVI). Materials and methods. The study included 744 patients with stable IHD forms who were being prepared for elective surgical myocardial revascularization. Exclusion criteria were ACS within less than one month; atrial fibrillation rhythm; and the brachial-ankle index <0.9. The group for analysis consisted of 374 patients (50.3 %). Volume sphygmography was performed using the VaSera-1000 instrument (Fukuda Denschi, Japan). Based on CAVI values, patients were divided into three groups: group I (n=141), patients with normal CAVI (<8.0), group II (n=129), patients with intermediate CAVI (≥8 and ≤9.0), and group III (n=104), patients with abnormal CAVI (>9.0). The groups were compared by clinico-historical and laboratory data, results of EchoCG, color duplex scanning of brachiocephalic arteries (BCA) and lower limb arteries, and coronary angiography (CAG). Results. The groups differed in age (р=0.000), presence of arterial hypertension (AH) (р=0.002), AH duration (р=0.017), smoking status (р=0.002), and type 2 diabetes mellitus (DM) (р=0.029). The rate of BCA stenosis was significantly higher in patients of groups III and II than in group I. The highest percentage of BCA stenosis was observed in group III; group I significantly differed from group II, and group II significantly differed from group III. Two coronary vessels were affected more frequently in IHD patients with normal and intermediate CAVI values and less frequently in patients with abnormal CAVI. Correlation analysis showed significant correlations of CAVI with left atrial dimensions and LV myocardial mass index. Conclusion. In patients with stable IHD, normal CAVI values were observed in 37.7 % of cases, intermediate in 34.5 % of cases, and abnormal in 27.8 % of cases. Patients with abnormal CAVI were older and had higher rates of AH, DM, and stenosis of non-coronary arteries. The presence of abnormal CAVI was associated with increased left atrial dimensions, aortic diameter, myocardial mass index, and LV relative thickness.
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Sumin A. N., Osokina A. V., Shcheglova A. V. et al. EchoCG data in ihd patients with different cardio-ankle vascular indexes. Russian Heart Journal. 2015;14 (3):123–130

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