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Heart rhythm variability in patients with essential hypertension after acute cerebrovascular disease

Polupanov A. G., Dzhumagulova A. S., Romanova T. A., Cheskidova N. B.

Keywords: heart rate variability, ischemic stroke, tilt test, essential hypertension

DOI: 10.18087/rhj.2014.4.1945

Background. Inconsistent results from studies of heart rhythm variability (HRV) in hypertensive patients, especially with regard to the range of HRV spectrum low-frequency component, determine the topicality of studies in this field. Aim. To study HRV in patients with essential hypertension (EH) after acute cerebrovascular disease. Materials and methods. We studied HRV in 16 EH patients who had had ischemic stroke 0.5–3 years before the enrollment in the study. Control group included 53 patients with uncomplicated EH (without stroke and myocardial disease, i.e., LV hypertrophy). HRV was assessed using the Holter ECG monitoring system “Memoport 2000”. Results. Evaluation of the autonomic nervous system (ANS) in EH patients after ischemic stroke detected significant decreases in the power of all HRV spectral characteristics (TP, VLF, LF, HF). In this group of patients, the tilt test reduced power of the LF component, which suggested a disadaptive (abnormal) response to verticalization of the ANS sympathetic part. Conclusion. The disadaptive response of LF component to the orthostatic test may represent a prognostically unfavorable sign of developing cerebrovascular complications in EH patients.
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Polupanov A.G., Dzhumagulova A.S., Romanova T.A. et al. Heart rhythm variability in patients with essential hypertension after acute cerebrovascular disease. Russian Heart Journal. 2014;78 (4):256–260

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