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Psychosomatic and gender features of multifocal atherosclerosis in patients with ischemic heart disease

Sumin A. N., Korok E. V., Raykh O. I., Gayfulin R. A., Bezdenezhnykh A. V., Barbarash O. L.

Keywords: atherosclerosis, gender peculiarities, CAD, psychosomatics

DOI: 10.18087/rhj.2014.2.1892

Background. Presence of atherosclerotic damage to non-cardiac arterial bed is prognostically unfavorable in patients with IHD. Although gender differences in risk factors (RFs) and clinical manifestations of atherosclerosis are well known, these differences are still understudied in patients with multifocal atherosclerosis (MFA). Effects of gender on the relationship of personality type, psychosocial factors and presence of MFA have not been studied so far. Aim. To study prevalence of personality types and features of psychological status in relation to the presence of MFA and the gender. Materials and methods. The study included 709 patients who have an undergone elective coronary bypass (CB) surgery. Based on the gender and MFA signs, 4 groups were formed: group 1, women without MFA (n=108); group 2, women with MFA (n=23); group 3, men without MFA (n=471); and group 4, men with MFA signs (n=107). Coronary angiography and evaluation of psychological status were performed for all patients before CB. Results. One-vessel coronary disease was more common in men (р=0.040). Three-vessel coronary disease prevailed in women without signs of MFA (33.3 %, р<0.05). Type D personality was more frequent in both men (43.9 %) and women (52.2 %) in the presence of MFA than in isolated coronary disease (17 and 15.9 %, respectively, р<0.05). Both male and female patients with signs of MFA had higher levels of negative excitability, social inhibition, depression, and anxiety than patients with isolated coronary disease (р<0.05). General health condition, physical and mental health, pain intensity, and vitality were lower in patients with MFA than without MFA (р<0.05). Furthermore, the emotional condition as higher in women without signs of MFA than in men (р=0.011). Conclusion. Type D personality was observed more frequently in both male and female IHD patients with MFA than without MFA (р<0.05). The found interrelationship of type D personality and MFA may represent a mechanism for the unfavorable effect of type D personality on prognosis in IHD patients.
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Sumin A. N., Korok E. V., Raykh O. I. et al. Psychosomatic and gender features of multifocal atherosclerosis in patients with ischemic heart disease. Russian Heart Journal. 2014;76 (2):74–80

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