2014


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2014/№1

Non-conventional risk factors: Clinical and functional significance in progression of chronic obstructive pulmonary diseases and arterial hypertension

Vasilkova T. N., Mataev S. I., Sorokin D. V., Rybina Yu. A., Baklaeva T. B.

Keywords: hyperpiesis, non-conventional risk factors, chronic obstructive pulmonary disease

DOI: 10.18087/rhj.2014.1.1894

Background. In recent years, the scientific literature has paid growing attention to non-conventional risk factors (RFs), including psycho-social RFs for comorbid cardiorespiratory diseases. Aim. To study the role of psycho-social RFs in progression of chronic obstructive pulmonary disease (COPD) combined with essential hypertension (EH). Materials and methods. 82 patients (age 55-59 years) with moderate COPD at the incomplete remission phase and 2nd stage EH were evaluated and divided into two groups: group 1 included 49 patients with COPD and group 2 consisted of 33 patients with COPD associated with EH. The assessed parameters included body mass index (BMI), smoker index (SI), degree of alcohol abuse, family and social status (education), depression by the Hamilton scale, asthenic syndrome, and quality of life (QoL). Results. Combined cardiorespiratory disease was associated with a high prevalence of negative behavioral characteristics, such as alcohol abuse (54.0%), long-term smoking (23.7±2.1 years), SI>10, and BMI>25 as distinct from patients with isolated COPD. The combination of COPD and EH was characterized by a high incidence of high-grade non-conventional (psycho-social) RFs, including low educational status, high proportion of bachelors, pronounced asthenic and anxiety depressive disorders and their components (sleep disorders, hostility, vital exhaustion) associated with low QoL scores. Conclusion. The found correlations between clinical and functional parameters and non-conventional RFs prove the RF adverse effect on progression of both COPD and EH.
  1. Евдокимова А. А., Мамедов М. Н., Шальнова С. А. и др. Оценка распространённости факторов риска и определение суммарного сердечно-сосудистого риска в случайной городской выборке мужчин и женщин. Профилактическая медицина. 2010;2:3–8.
  2. Оганов Р. Г., Масленникова Г. Я. Демографическая ситуация и сердечно-сосудистые заболевания в России: пути решения проблем Кардиоваскулярная терапия и профилактика. 2007;6:7–14.
  3. Чучалин А. Г. Клинические рекомендации по лечению больных хронической обструктивной болезнью легких [под ред. А. Г. Чучалина]. – Москва: Изд-во BINOM, 2007. – 225 с.
  4. Шальнова С. А., Деев А. Д. Характеристика пациентов высокого риска. Результаты эпидемиологической части научно-образовательной программы ОСКАР. Кардиоваскулярная терапия и профилактика. 2006;6:58–63.
  5. Василькова Т. Н., Попова Т. Н., Медведева И. В. Метаболический синдром и бронхообструкция – две составляющие системного воспаления. Врач. 2008;8:19–22.
Vasilkova T. N., Mataev S. I., Sorokin D. V. et al. Non-conventional risk factors: Clinical and functional significance in progression of chronic obstructive pulmonary diseases and arterial hypertension. Russian Heart Journal. 2014;75 (1):53–58

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