2013


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2013/№5

Time-dependent changes in parameters of mitral regurgitation in patients with myocardial infarction

Zhelnov V.V., Komarova I.S., Andreeva N.V., Shcheglova Yu.M.
State Budgetary Educational Institution “I. M. Sechenov First Moscow State Medical University” of the RF Ministry of Health Care, Trubetskaya 8, Bld. 2, Moscow 119991

Keywords: diagnostics, myocardial infarction, mitral regurgitation, EchoCG

DOI: 10.18087/rhj.2013.5.1828

Background. In patients with acute MI, ischemic mitral regurgitation (IMR) is an independent predictor of death as distinct from the infarct size and the LV EF value. Aim. To study time-dependent changes in IMR parameters and mitral valve (MV) structures in patients with MI and IRM. Materials and methods. 150 patients aged from 39 to 80 years (64.2±6.1 years) admitted with Q-MI in the first 24 hours of disease onset were evaluated. All patients underwent Doppler echoCG examination with quantification of regurgitation parameters and MV structural deformation (using Q-DE and PISA methods) at 2 and 20 days. Results. Analysis of changes in individual parameters revealed three groups of patients. Parameters of mitral regurgitation and MV structural deformation increased in 37.3 % of patients, decreased in 42.7 % of patients and remained unchanged in 20 % of patients. Conclusion. The obtained data evidence the dynamic nature of IMR in 80 % of patients with Q-MI in the first 20 days of disease.
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helnov V.V., Komarova I.S., Andreeva N.V. et al. Time-dependent changes in parameters of mitral regurgitation in patients with myocardial infarction. Russian Heart Journal. 2013;12(5):282-286

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