Clinical and prognostic significance of hypoglycaemia events in patients with myocardial infarction with ST segment elevation in combination with diabetes mellitus type 2
Karetnikova V. N., Belenkova Yu. A., Zykov M. V., Kashtalap V. V., Zhaleev B. Z., Barbarash O. L.
Keywords: hypoglycemia, myocardial infarction, ST segment elevation, type 2 diabetes mellitus
Relevance. Important aspect glycemic control in MI patients in combination with DM type 2 are hypoglycemia prevention. Objective. Evaluation of clinical and prognostic importance of hypoglycemia events in patients with MI with ST segment elevation against DM type 2. Materials and methods. The study included 77 patients with MI with ST segment elevation against DM type 2. Definition glycemic profile, including level glycemia evaluation at night and early morning hours (3.00 and 5.00 a.m.) were performed in all patient on days 6–10 from MI onset. Results. In this study, hypoglycemia events were registered 27 patients (35.07 %). No distinctions were revealed inthe course of hospitalization in patients with and without hypoglycemia. The analysis of hypoglycemia influence on the annual forecast for MI patients showed significant increase in number of the majority of adverse cardiovascular events. Conclusion. Hypoglycemia has more prognostic, than clinical significance. Considering adverse effect of hypoglycemia in MI patients with DM on the long-term forecast, it is necessary to consider spontaneous hypoglycemia as display (marker) of severe illness with adverse forecast.
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Karetnikova V. N., Belenkova Yu. A., Zykov M. V. et al. Clinical and prognostic significance of hypoglycaemia events in patients with myocardial infarction with ST segment elevation in combination with diabetes mellitus type 2. Russian Heart Journal. 2013;12(1):33-36