Peculiarities of the parenteral anticoagulant treatment in common cardiovascular diseases
Article reflects major peculiarities of practical application of available parenteral anticoagulants. While many medications of this group are now at different stages of development, only heparin formulations, direct-action thrombin inhibitors, vitamin K and relatively recent fondaparincus sodium (hereinafter referred as fondaparincus) have been approved for wide application. Article analyses in detail pharmacological properties of parenteral anticoagulants and relevance of parenteral anticoagulants for prevention of lower extremity deep vein thrombosis and pulmonary thromboembolism in non-surgical patients. New data on the use of parenteral anticoagulants in acute coronary syndromes are presented.