Russian Heart Failure Journal 2014year Pneumonia in hospitalized patients with circulatory decompensation (Pavlov Hospital Registry)

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Pneumonia in hospitalized patients with circulatory decompensation (Pavlov Hospital Registry)

Arutyunov A. G., Rylova A. K., Arutyunov G. P.
State Budgetary Educational Institution of Higher Professional Education, “N.I. Pirogov Russian National Research Medical University” of the RF Ministry of Health Care, Ostrovityanova 1, Moscow 117997

Keywords: circulatory decompensation, pneumonia, register

DOI: 10.18087/rhfj.2014.3.1955

Background. Universal ageing of the population, success of medicine in treatment of cardiovascular diseases, and prolonged life expectancy resulted in prevalence of patients with high comorbidity. A combination of two or more diseases, for example, CHF and pneumonia, considerably worsens the life prognosis. Aim. To study the effect of concurrent CHF and pneumonia on early and remote prognoses in real-life clinical practice. Materials and methods. Data of patients with decompensated CHF and pneumonia included in the Pavlov Hospital Registry were analyzed. Results. Pneumonia was diagnosed in 317 CHF patients. 301 patients had community-acquired pneumonia and 16 patients had nosocomial pneumonia; women were diagnosed with pneumonia twice as frequently as men. A considerable proportion of patients had no typical signs of pneumonia onset, such as leukocytosis and fever, and severity of the condition was primarily determined by pronounced comorbidities. The death rate of patients with pneumonia was 45.7% for one year. The highest risk of fatal outcome was associated with the following phenotypes: pneumonia + chronic kidney disease (CKD), pneumonia + anemia + CKD, pneumonia + lean body mass deficiency, pneumonia + changed antibacterial therapy. Conclusion. In patients with circulatory decompensation, pneumonia is always severe; it aggravates CHF, and considerably increases the risk of fatal outcome.
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Arutyunov A.G., Rylova A.K., Arutyunov G.P. Pneumonia in hospitalized patients with circulatory decompensation (Pavlov Hospital Registry). Russian Heart Failure Journal. 2014;84 (3):146–159

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