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Registry of hospitalized patients with circulatory decompensation (Pavlov Registry). Report 1. Current clinical characteristics of a patient with circulatory decompensation. Clinical phenotypes of patients

Arutyunov A. G., Rylova A. K., Arutyunov G. P.
State Budgetary Educational Institution of Higher Professional Education, “N.I. Pirogov Russian National Research Medical University” of the RF Ministry of Health Care, Ostrovityanova 1, Moscow 117997

Keywords: circulatory decompensation, epidemiology

DOI: 10.18087/rhfj.2014.1.1933

Background. Prognosis in patients admitted for circulatory decompensation remains very severe. Development of a method for grading patients with circulatory decompensation based on major clinical signs (identification of patient phenotypes) will allow evaluating the effect of decompensation correction and remote results of treatment. Aim. To create a registry for analyzing the clinical portrait of a present-day patient with circulatory decompensation in real-life clinical practice. Materials and methods. The registry included patients older than 18 with a history of symptomatic congestive HF and signs of circulatory decompensation. The observation lasted for 23.4±13.8 months. At 30, 90, 180, and 365 days of discharge from the hospital, the number of rehospitalizations, therapy, patient’s activity, body weight, and heart rate (HR) were recorded. In case of fatal outcome the cause of death was recorded. 1001 patients were enrolled; 482 patients were included into the final analysis. Results. The clinical portrait of a patient with circulatory decompensation has considerably changed in recent years. Older women prevail among the patients; more than a half of patients have preserved LV EF; most of the patients receive a therapy which does not completely meet current guidelines; and the absolute majority of patients is characterized with pronounced comorbidity. Conclusion. It is necessary to identify several phenotypes of patients with circulatory decompensation based on the patient’s comorbidity.
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Arutyunov A. G., Rylova A. K., Arutyunov G. P. Registry of hospitalized patients with circulatory decompensation (Pavlov Registry). Report 1. Current clinical characteristics of a patient with circulatory decompensation. Clinical phenotypes of patients. Russian Heart Failure Journal. 2014;15(1):23–31

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