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Cardiorenal syndrome at decompensated heart failure

Shchekochikhin D. Yu., Kopylov F. Yu., Kozlovskaya N. L., Syrkin A. L.
State Budgetary Educational Institution “I. M. Sechenov First Moscow State Medical University” of the RF Ministry of Health Care, Trubetskaya 8, Bld. 2, Moscow 119991

Keywords: cardiorenal syndrome, chronic kidney disease, CHF

DOI: 10.18087/rhfj.2012.4.1697

Recent data have shown exceptional importance of cardiorenal relation disorders at stable CHF and decompensation, which allowed to speak about cardiorenal syndrome (CRS). Cardiorenal syndrome is an extracardiac presentation of the disease. Chronic “subfullness” of the arterial channel with subsequent neurohumoral activation, systemic and nephritic vasoconstriction promotes changes of GFR in response to the hemodynamic changes and development of acute nephritic lesion influenced by nephrotoxic agents and endotoxins.
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Shchekochikhin D. Yu., Kopylov F. Yu., Kozlovskaya N. L. et al. Cardiorenal syndrome at decompensated heart failure. Russian Heart Failure Journal. 2012;13(4):248-252

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