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Role of Tei-index in evaluation of arterial hypertension therapy effectiveness

Vasyuk Yu. A., Khadzegova A. B., Ivanova S. V., Yushuk E. N., Amirbigshvili I. M., Matveeva O. S., Schupenina E. Yu., Khuchivaeva A. M., Nadina E. V., Sinitsyna I. A., Sadulaeva I. A.

Keywords: arterial hypertension, diastolic dysfunction of the left ventricle, myocardium performance index, EchoCG

DOI: 10.18087/rhfj.2012.3.1702

Relevance. It was found that patients with arterial hypertension along with diastolic LV often have also the impairment of systolic function. Having this in mind, it seems that separate evaluation of systolic and diastolic dysfunction could be rather questionable. It’s more appropriate to speak about the functional state of LV and right ventricular (RV) conjointly. On the background of the effective antihypertensive therapy improvement of systolic and diastolic function occurs, that might be evaluated with the help of the cardiac performance index. Objective. To determine the role of the ventricle performance index (Tei-index) in the evaluation of effectiveness of the antihypertensive therapy. Materials and methods. The study included 88 AH Patients (21 men, 67 women) and 24 healthy volunteers (9 men and 15 women). Diurnal monitoring of arterial pressure (APDM), two-dimensional EchoCG, Doppler EchoCG and tissue Doppler EchoCG. Results. In AP patients peak E speeds of LV and RV, as well as the value of ratio E / A of trans-mitra and transtricuspidal flows on the background of 6‑month antihypertensive therapy were not changed reliably whereas reliable dynamics of time values of transmitral and transtricuspidal flows were observed. In AH patients reduction of the Tei-index of LV due to reduction of duration of isovoluminous reduction in absence of reliable dynamics of speed values of transmitral blood flow testifies about improvement of the LV functional state. On the background of the conducted therapy values of regional Tei-index in the interventricular septum and the lateral wall of LV are reliably reducing, which testifies improvement of the functional state of corresponding LV walls. The analogous dynamics of Tei-index has place in the area of free wall of RV at the level of the tricuspidal ring. Conclusion. Reduction of Tei-index both global, evaluated by transmitral blood flow and regional, evaluated by tissue dopplerography of atrio-ventricular rings, is the earliest marker of LV and RV myocardium functional state improvement and it confirms the effect of the antihypertensive therapy conducted.
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Vasyuk Yu. A., Khadzegova A. B., Ivanova S. V. et al. Role of Tei-index in evaluation of arterial hypertension therapy effectiveness. Russian Heart Failure Journal. 2012;13(3):162-166

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