2012


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2012/№2

Right ventricle filling indices in healthy people of different age

Sumin A. N., Arkhipov O. G.

Keywords: age, right ventricular diastolic dysfunction

DOI: 10.18087/rhfj.2012.2.1617

Relevance. Prognostic value of RV diastolic dysfunction, its interrelation with HF clinical presentations and exercise tolerance are well-known. Due to age-related natural deterioration of compliance of the chambers of heart and depression of ventricle diastolic functions, there is a problem of differentiation between pathological and age-specific changes of RV diastolic function. Objective. Study in different age groups of RV diastolic function indices, including intraventricular propagation of early transtricuspid flow. Materials and methods. The study included 270 patients (129 male) at the age of 13 to 83 years (average age 45.3±0.9 years). The following groups were made: under 20 years, 20–29 years, 30–39 years, 40–49 years, 50–59 years, 60–69 years, 70 years and older. The subjects underwent EchoCG (Medison Sonacе 8 000 apparatus). Early (Eат) and late (Aат) tricuspid annular diastolic velocities, and their ratio (Eат/ Aат) was measured by tissue Doppler echocardiography; early transtricuspid flow velocity (Eт), atrial systole flow (Aт), and their ratio (Eт / Aт). RV filling flow velocity was measured (tricuspid flow velocity) in the combined color M-mode. Results. Eат index in the first three groups did not differ much, in the groups above 40 years old, a linear reduction of Eат by 1.5–2 cm / sec (by 10–15 %) per every ten years was observed (р=0.00001). On the contrary, Aat velocity increased significantly in subject older 50 years (р=0.00001). Eат / Aат ratio reduced linearly from the age of 30 by 8–15 % per every ten years from 1.6 to 0.75 (р=0.00001). Tricuspid flow velocity index reduced from 48.5 cm / sec in subjects under 20 years by 1–3 cm / sec per every ten years (р=0.00001). Conclusion. As healthy people grow older, natural deterioration of RV diastolic function index is observed. This was manifested by decrease of the early and late systolic transtricuspid flow velocity ratio, early and late systolic tricuspid annular diastolic velocities and RV early diastolic flow velocity. Moderate correlation between different examined indices of RV diastolic function indicates different diastole parameters evaluated by them. Comprehensive RV diastolic function assessment is advisable taking into account age-related changes of indices.
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Sumin A. N., Arkhipov O. G. Right ventricle filling indices in healthy people of different age. Russian Heart Failure Journal. 2012;13(2):73-78

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