Russian Heart Failure Journal 2010year Acetazolamide in cardiology practice: clinical experience and evidence base


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2010/

Acetazolamide in cardiology practice: clinical experience and evidence base

Gilyarevskiy S. R., Orlov V. A., Golshmid M. V., Zakharova G. Y., Sinitsina I. I.

Keywords: acetazolamide, chronic obstructive pulmonary disease, CHF, central sleep apnea

DOI: 10.18087/rhfj.2010.6.1443

This review presents possible indications for acetazolamide prescription. It is used in CHF in order to overcome resistance to loop diuretics, for treatment of central sleep apnea. The beneficial effect of acetazolamide on blood gas composition is shown in patients with hypercapnia due to COPD. Acetazolamide is effective for prevention of cardiovascular complications of high-altitude illness. Test with acetazolamide is used for assessment of cerebral blood flow. However, to refine the tactics of acetazolamide usage, as well as other diuretics in CVD treatment, randomized clinical trials conducting is necessary.
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Gilyarevskiy S. R., Orlov V. A., Golshmid M. V. et al. Acetazolamide in cardiology practice: clinical experience and evidence base. Russian Heart Failure Journal. 2010;11(6):375-381.

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