Russian Heart Failure Journal 2010year Stress cardiomyopathy or takotsubo cardiomyopathy

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Stress cardiomyopathy or takotsubo cardiomyopathy

Gilyarevskiy S. R., Kosolapov D. A., Lopotovskiy P. Y., Kuzmina I. M., Avdeeva I. Y., Antonik E. Y., Baturina O. V.

Keywords: cardiomyopathy, takotsubo

DOI: 10.18087/rhfj.2010.5.1404

The paper addresses clinical manifestation, diagnostic and therapeutic possibilities in the presence of stress cardiomyopathy syndrome (SCMP). Case report from own clinical practice in elder women is presented.
  1. Sharkey SW, Lesser JR, Zenovich AG et al. Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation. 2005;111 (4):472–479.
  2. Sato H, Tateishi H, Uchida T et al. Tako-Tsubo – like left ventricular dysfunction due to multivessel coronary spasm. In: Kodama K, Haze K, Hori M, editors. Clinical aspect of myocardial injury: from ischemia to heart failure (in Japanese). Tokyo: Kagakuhyoronsha Publishing Co; 1990. p. 56–64.
  3. Cimarelli S, Sauer F, Morel O et al. Transient left ventricular dysfunction syndrome: Patho-physiological bases through nuclear medicine imaging. Int J Cardiol. 2009 May 12. [Epub ahead of print]. Available at:
  4. Desmet WJ, Adriaenssens BF, Dens JA. Apical ballooning of the left ventricle: first series in white patients. Heart. 2003;89 (9):1027–1031.
  5. Bybee K. A, Prasad A, Barsness G et al. Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome. Am J Cardiol. 2004;94 (3):343–346.
  6. Elian D, Osherov A, Matetzky S et al. Left ventricular apical ballooning: not an uncommon variant of acute myocardial infarction in women. Clin Cardiol. 2006;29 (1):9–12.
  7. Pilliere R, Mansencal N, Digne F et al. Prevalence of Tako-Tsubo syndrome in a large urban agglomeration. Am J Cardiol. 2006;98 (5):662–665.
  8. Parodi G, Del Pace S, Carrabba N et al. Incidence, clinical findings, and outcome of women with left ventricular apical ballooning syndrome. Am J Cardiol. 2007;99 (2):182–185.
  9. Azzarelli S, Galassi AR, Amico F et al. Clinical features of transient left ventricular apical ballooning. Am J Cardiol. 2006;98 (9):1273–1276.
  10. Larson DM, Menssen KM, Sharkey SW et al. «False-positive» cardiac catheterization laboratory activation among patients with suspected ST-segment elevation myocardial infarction. JAMA. 2007;298 (23):2754–2760.
  11. Prasad A, Lerman A, Rihal CS. Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J. 2008;155 (3):408–417.
  12. Bybee KA, Kara T, Prasad A et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med. 2004;141 (11):858–865.
  13. Gianni M, Dentali F, Grandi AM et al. Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J. 2006;27 (13):1523–1529.
  14. Kneale BJ, Chowienczyk PJ, Brett SE et al. Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculature. J Am Coll Cardiol. 2000;36 (4):1233–1238.
  15. Wittstein IS, Thiemann DR, Lima JA et al. Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med. 2005;352 (6):539–548.
  16. Lacy CR, Contrada RJ, Robbins ML et al. Coronary vasocontriction induced by mental stress. Am J Cardiol. 1995;75 (7):503–505.
  17. Sadamasu K, Tashiro H, Maehira N, Yamamoto K. Coronary microvascular abnormality in the reversible dysfunction observed after nocardiac disease. Jpn Circ J. 2000;64 (10):789–792.
  18. Singal PK, Kapur N, Dhillon KS et al. Role of free radicals in catecholamine-induced cardiomyopathy. Can J Physiol Pharmacol. 1982;60 (11):1390–1397.
  19. Braunwald E, Kloner R. A. Myocardial reperfusion: a double-edged sword? J Clin Invest. 1985;76 (5):1713–1719.
  20. Nef HM, Möllmann H, Kostin S et al. Tako-Tsubo cardiomyopathy: intraindividual structural analysis in the acute phase and after functional recovery. Eur Heart J. 2007 Oct; 28 (20):2456–2464.
  21. Duflou J, Nickols G, Waite P et al. Artefactual contraction band necrosis of the myocardium in fatal air crashes. Aviat Space Environ Med. 2006;77 (9):944–949.
  22. Mori H, Ishikawa S, Kojima S et al. Increased responsiveness of left ventricular apical myocardium to adrenergic stimuli. Cardiovasc Res. 1993;27 (2):192–198.
  23. Elesber A, Prasad A, Lennon R et al. Four-year recurrence rate and prognosis of the apical ballooning syndrome. J Am Coll Cardiol. 2007;50 (5):448–452.
  24. Sato M, Fujita S, Saito A et al. Increased incidence of transient left ventricular apical ballooning (so-called ‘Takotsubo’ cardiomyopathy) after the mid-Niigata Prefecture earthquake. Circ J. 2006;70 (8):947–953.
  25. Akashi YJ, Sakakibara M, Miyake F. Reversible left ventricular dysfunction «takotsubo» cardiomyopathy associated with pneumothorax. Heart. 2002;87 (2):E1.
  26. Rajani R, Przedlacka A, Saha M, de Belder A. Pancreatitis and the broken heart. Eur J Emerg Med. 2010;17 (1):27–29.
  27. Stöllberger C, Huber JO, Enzelsberger B, Finsterer J. Fatal outcome of epileptic seizure-induced takotsubo syndrome with left ventricular rupture. Eur J Neurol. 2009;16 (6):e116–117.
  28. Arora S, Alfayoumi F, Srinivasan V. Transient left ventricular apical ballooning after cocaine use: is catecholamine cardiotoxicity the pathologic link? Mayo Clin Proc. 2006;81 (6):829–832.
  29. Bergman BR, Reynolds HR, Skolnick AH, Castillo D. A case of apical ballooning cardiomyopathy associated with duloxetine. Ann Intern Med. 2008;149 (3):218–219.
  30. Rivera JM, Locketz AJ, Fritz KD et al. «Broken heart syndrome» after separation (from OxyContin). Mayo Clin Proc. 2006;81 (6):825–828.
  31. Dorfman T, Aquel R, Allred J et al. Takotsubo cardiomyopathy induced by treadmill exercise testing: an insight into the pathophysiology of transient left ventricular apical (or midventricular) ballooning in the absence of obstructive coronary artery. J Am Coll Cardiol. 2007;49 (11):1223–1225.
  32. Rossor AM, Pearce SH, Adams PC. Left ventricular apical ballooning (Takotsubo cardiomyopathy) in thyrotoxicosis. Thyroid. 2007;17 (2):181–182.
  33. Tsuchihashi K, Ueshima K, Uchida T et al. Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol. 2001;38 (1):11–18.
  34. Bybee K, Motiei A, Syed I et al. Electrocardiography cannot reliably differentiation of transient left ventricular apical ballooning syndrome from anterior ST-segment elevation myocardial infarction. J Electrocardiol. 2007;40 (1):38.e1–6.
  35. Ogura R, Hiasa Y, Takahashi T et al. Specific findings of the standard 12‑lead ECG in patients with ‘Takotsubo’ cardiomyopathy: comparison with the findings of acute anterior myocardial infarction. Circ J. 2003;67 (8):687–690.
  36. Kurisu S, Inoue I, Kawagoe T et al. Time course of electrocardiographic changes in patients with Tako-Tsubo syndrome: comparison with acute myocardial infarction with minimal enzymatic release. Circ J. 2004;68 (1):77–81.
  37. Matsuoka K, Okubo S, Fujii E et al. Evaluation of the arrhythmogenecity of stress-induced «Takotsubo cardiomyopathy» from the time course of the 12‑lead surface electrocardiogram. Am J Cardiol. 2003;92 (2):230–233.
  38. Mahida S, Dalageorgou C, Behr ER. Long-QT syndrome and torsades de pointes in a patient with Takotsubo cardiomyopathy: an unusual case. Europace. 2009;11 (3):376–378.
  39. Akashi YJ, Musha H, Nakazawa K, Miyake F. Plasma brain natriuretic peptide in Takotsubo cardiomyopathy. QJM. 2004;97 (9):599–607.
  40. Elesber AA, Prasad A, Bybee KA et al. Transient cardiac apical ballooning syndrome: prevalence and clinical implications of right ventricular involvement. J Am Coll Cardiol. 2006;47 (5):1082–1083.
  41. Haghi D, Athanasiadis A, Papavassiliu T et al. Right ventricular involvement in Takotsubo cardiomyopathy. Eur Heart J. 2006;27 (20):2433–2439.
  42. Haghi D, Papavassiliu T, Fluchter S et al. Variant form of the acute apical ballooning syndrome (takotsubo cardiomyopathy): observations on a novel entity. Heart. 2006;92 (3):392–394.
  43. Hurst RT, Askew JW, Reuss CS et al. Transient midventricular ballooning syndrome: a new variant. J Am Coll Cardiol. 2006;48 (3):579–583.
  44. Haghi D, Fluechter S, Suselbeck T et al. Cardiovascular magnetic resonance findings in typical versus atypical forms of the acute apical ballooning syndrome (Takotsubo cardiomyopathy). Int J Cardiol. 2007;120 (2):205–211.
  45. Mitchell JH, Hadden TB, Wilson JM et al. Clinical features and usefulness of cardiac magnetic resonance imaging in assessing myocardial viability and prognosis in Takotsubo cardiomyopathy (transient left ventricular apical ballooning syndrome). Am J Cardiol. 2007;100 (2):296–301.
  46. Deetjen AG, Conradi G, Mollmann S et al. Value of gadolinium-enhanced magnetic resonance imaging in patients with Tako-Tsubo – like left ventricular dysfunction. J Cardiovasc Magn Reson. 2006;8 (2):367–372.
  47. Park JH, Kang SJ, Song JK et al. Left ventricular apical ballooning due to severe physical stress in patients admitted to the medical ICU. Chest. 2005;128 (1):296–302.
  48. Haghi D, Fluechter S, Suselbeck T et al. Takotsubo cardiomyopathy (acute left ventricular apical ballooning syndrome) occurring in the intensive care unit. Intensive Care Med. 2006;32 (7):1069–1074.
  49. Prasad A. Apical ballooning syndrome: an important differential diagnosis of acute myocardial infarction. Circulation. 2007;115 (5):e56–59.
  50. Lee VH, Connolly HM, Fulgham JR et al. Tako-Tsubo cardiomyopathy in aneurysmal subarachnoid hemorrhage: an underappreciated ventricular dysfunction. J Neurosurg. 2006;105 (2):264–270.
  51. Lee VH, Oh JK, Mulvagh SL, Wijdicks EF. Mechanisms in neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2006;5 (3):243–249.
  52. Donahue D, Movahed MR. Clinical characteristics, demographics and prognosis of transient left ventricular apical ballooning syndrome. Heart Fail Rev. 2005;10 (4):311–316.
  53. Zenovich AG. Стрессовая кардиомиопатия как заболевание, которое должны учитывать кардиологи при проведении дифференциальной диагностики. Доказательная кардиология. 2005;2:28–29.
  54. Akashi YJ, Tejima T, Sakurada H et al. Left ventricular rupture associated with Takotsubo cardiomyopathy. Mayo Clin Proc. 2004;79 (6):821–824.
  55. Ohara Y, Hiasa Y, Hosokawa S et al. Left ventricular free wall rupture in transient left ventricular apical ballooning. Circ J. 2005;69 (5):621–623.
  56. Shinozaki K, Tamura A, Abe Y et al. Left ventricular free wall rupture in takotsubo cardiomyopathy. Int J Cardiol. 2007;115 (1):e3–4.
  57. Ishida T, Yasu T, Arao K et al. Images in cardiovascular medicine. Bedside diagnosis of cardiac rupture by contrast echocardiography. Circulation. 2005;112 (24):e354–355.
  58. Parodi G, Del Pace S, Salvadori C et al. Tuscany Registry of Tako-Tsubo Cardiomyopathy. Left ventricular apical ballooning syndrome as a novel cause of acute mitral regurgitation. J Am Coll Cardiol. 2007;50 (7):647–649.
  59. Eitel I, Lücke C, Behrendt F et al. Full recovery of Takotsubo cardiomyopathy (apical ballooning) in two days. Int J Cardiol 2009. Available at:
  60. Sharkey SW, Shear W, Hodges M, Herzog CA. Reversible myocardial contraction abnormalities in patients with an acute noncardiac illness. Chest. 1998;114 (1):98–105.
  61. Kimura K, Tanabe-Hayashi Y, Noma S, Fukuda K. Rapid formation of left ventricular giant thrombus with Takotsubo cardiomyopathy. Circulation. 2007;115 (23):e620–621.
  62. Гиляров М. Ю., Сафарова М. С., Сыркин А. Л. Стресс-индуцированная кардиомиопатия (синдром тако-цубо). Кардиология в сердечно-сосудистой хирургии. 2008;2:69–75.
Gilyarevskiy S. R., Kosolapov D. A., Lopotovskiy P. Y. et al. Stress cardiomyopathy or takotsubo cardiomyopathy. Russian Heart Failure Journal. 2010;11(5):306-314.

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