Russian Heart Failure Journal 2009year Beta-adrenoblockers and the renal continuum

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Beta-adrenoblockers and the renal continuum

Arutyunov G. P., Oganezova L. G.



Chronic heart failure is often associated with renal dysfunction. An important pathogenetic component of these conditions is overactivation of the sympathico-adrenal system (SAS). Thus the present review discusses the issue of efficacy and safety of β-adrenoblockers (BAB) in this patient population. Review provides results of the largest studies (COMET, PRIME-II, SOLVD Prevention and Treatment, CIBIS-II and CIBIS-III) evaluating the effect of BAB on prognosis in patients with CHF and chronic renal disease.
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