Russian Heart Failure Journal 2009year Cordial and extracardiac comorbidity in elderly and senile patients with systolic and diastolic chronic heart failure
Cordial and extracardiac comorbidity in elderly and senile patients with systolic and diastolic chronic heart failure
Keywords: diastolic CHF, comorbidity, old age, systolic CHF
Urgency. Results of physical examination does not let find out the difference between patients with systolic chronic heart failure (S-CHF) and dyastolic chronic heart failure (D-CHF). Aim. To compare frequency and nature of cordial and extracardiac comorbidity in elderly and senile patients. Materials and methods. Anamnesis, clinical data, results of examionation of 167 patients in Hospital of war veterans № 1 (Moscow) aged fom 65 to 99, hospitalised with CHF decompensation during the period since 2004 to 2007. Analise of medical documentation was concentratd on revelation of cordial and extracardiac disorders. Results. Patients with S-CHF are mostly men, smokers (40,7 %), alcohol abused (22,2 %), with significant exercise stress (sport or manual labour in 9,9 %), with MI in anamnesis (85,2 %), including recurring (33,3 %). Patients with D-CHF are mostly women with marked metabolic disorders (overweight or obesity, diabetus mellitus or impaired glucose tolerance), mostly with arterial hypertension (76,7 %). Among patients with D–CHF there were 2 times less patients with MI (37,2 %) and 6 times less with reccuring MI (5,8 %). As extracardiac disorders patients with S-CHF mostly have chronic obstructive pulmonary disease (34,6 %) and obliterating atherosclerosis of the lower extremities vessels (23,5 %), patients with D-CHF – pneumonia (23,6 %) and lower extremity varicose veins disease (40,7 %).
- Jessup M, Brozena S. Heart failure. N Engl J Med. 2003; 348 (20):2007–2018.
- Redfield MM, Jacobsen SJ, Burnett JC Jr et al. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003; 289 (2):194–202.
- McDermott MM, Feinglass J, Sy J, Gheorghiade M. Hospitalized congestive heart failure patients with preserved versus abnormal left ventricular systolic function: clinical characteristics and drug therapy. Am J Med. 1995; 99 (6):629–635.
- Pernenkil R, Vinson JM, Shah AS et al. Course and prognosis in patients > or =70 years of age with congestive heart failure and normal versus abnormal left ventricular ejection fraction. Am J Cardiol. 1997; 79 (2):216–219.
- Vasan RS, Larson MG, Benjamin EJ et al. Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: prevalence and mortality in a population-based cohort. J Am Coll Cardiol. 1999; 33 (7):1948–1955.
- Dauterman KW, Go AS, Rowell R et al Congestive heart failure with preserved systolic function in a statewide sample of community hospitals. J Card Fail. 2001; 7 (3):221–228.
- Senni M, Tribouilloy CM; Rodeheffer R J et all. Congestive Heart Failure in the Community. A Study of All Incident Cases in Olmsted County, Minnesota, in 1991 Circulation. 1998; 98 (21):2282–2289.
- Беленков Ю. Н. Хроническая сердечная недостаточность в России – опыт 25 лет: где мы находимся и куда должны идти? Журнал сердечная недостаточность. 2003; 4 (1):9–11.
- Grandi AM, Zanzi P, Fachinetti A et al. Insulin and diastolic dysfunction in lean and obese hypertensives. Hypertension. 1999; 34 (6):1208–1214.
- Pitt B, Segal R, Martinez FA et al; on behalf of the ELITE investigators. Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Eldery Study, ELITE). Lancet. 1997; 349 (9054):747–752.
- Devereux RB, Roman MJ, Liu JE et al. Congestive heart failure despite normal left ventricular systolic function in a population-based sample: the strong heart study. Am J Cardiol. 2000; 86 (10):1090–1096.
- Jain A, Avendano G, Dharamsey S et al. Left ventricular diastolic function in hypertension and role of plasma glucose and insulin. Comparison with diabetic heart. Circulation. 1996; 93 (7):1396–1402.
- Palmieri V, Bella JN, Arnett DK et al. Effect of type 2 diabetes mellitus on left ventricular geometry and systolic function in hypertensive subjects: Hypertension Genetic Epidemiology Network (HyperGEN) study. Circulation. 2001; 103 (1):102–107.
- Cleland JG, Swedberg K, Follath F et al. The EuroHeart Failure survey programme a survey on the quality of care among patients with heart failure in Europe. Part 1: patients characteristics and diagnosis. Eur Heart J. 2003; 24 (5):442–463.
- Klapholz M, Maurer M, Lowe AM et al. Hospitalization for heart failure in the presence of a normal left ventricular ejection fraction: results of the New York Heart Failure Registry. J Am Coll Cardiol. 2004; 43 (8):1432–1438.
- Gray LK, Smyth KA, Palmer RM et al. Heterogeneity in older people: examining physiologic failure, age, and comorbidity. J Am Geriatr Soc. 2002; 50 (12):1955–1961.
- Bayliss EA, Bayliss MS, Ware JE Jr, Steiner JF. Predicting declines in physical function in persons with multiple chronic medical conditions: what we can learn from the medical problem list. Health Qual Life Outcomes. 2004; 2:47.
- Wolff JL, Starfield B, Anderson G. Prevalence, expenditures, and complications of multiple chronic conditions in the elderly. Arch Intern Med. 2002; 162 (20):2269–2276.
- Lien CT, Gillespie ND, Struthers AD, McMurdo ME. Heart failure in frail elderly patients: diagnostic difficulties, co-morbidities, polypharmacy and treatment dilemmas. Eur J Heart Fail. 2002; 4 (1):91–98.
- van der Wel MC, Jansen RW, Bakx JC et al. Non-cardiovascular co-morbidity in elderly patients with heart failure outnumbers cardiovascular co-morbidity. Eur J Heart Fail. 2007; 9 (6–7):709–715.
- Swedberg K, Cleland J, Dargie H et al. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Eur Heart J. 2005; 26 (11):1115–1140.
- Thomas JT, Kelly RF, Thomas SJ et al. Utility of history, physical examination, electrocardiogram, and chest radiograph for differentiating normal from decreased systolic function in patients with heart failure. Am J Med. 2002; 112 (6):437–445.
- Douglas PS, Katz SE, Weinberg EO et al. Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload. J Am Coll Cardiol. 1998; 32 (4):1118–1125.
- Sugden PH, Clerk A. Akt like a woman: Gender differences in susceptibility to cardiovascular disease. Circ Res. 2001; 88 (10):975–977.
- Olivetti G, Giordano G, Corradi D et al. Gender differences and aging: effects on the human heart. J Am Coll Cardiol. 1995; 26 (4):1068–1079.
- Kenchaiah S, Evans JC, Levy D et al. Obesity and the risk of heart failure. N Engl J Med. 2002; 347 (5):305–313.
- Iacobellis G, Ribaudo MC, Leto G et al. Influence of excess fat on cardiac morphology and function: study in uncomplicated obesity. Obes Res. 2002; 10 (8):767–773.
- Yusuf S, Hawken S, Ounpu S et al, on behalf of the INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART Study). Lancet. 2004; 364 (9438):937–952.
- Vasan RS, Benjamin EJ, Levy D. Prevalence, clinical features and prognosis of diastolic heart failure: an epidemiologic perspective. JJ Am Coll Cardiol. 1995; 26 (7):1565–1574.
- Tschöpe C, Bock CT, Kasner M et al. High prevalence of cardiac parvovirus B19 infection in patients with isolated left ventricular diastolic dysfunction. Circulation. 2005; 111 (7):879–886.
- Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function. Circulation. 2002; 105 (11):1387–1393.
- Lenzen MJ, Scholte op Reimer WJ, Boersma E et al. Differences between patients with a preserved and a depressed left ventricular function: a report from the EuroHeart Failure Survey. Eur Heart J. 2004; 25 (14):1214–1220.
- Lesman-Leegte I, Jaarsma T, Van Veldhuisen DJ. Quality of life in patients with preserved and depressed left ventricular function. Eur Heart J. 2005; 26 (5):525–526.
- Berry C, Hogg K, Norri J et al. Heart failure with preserved left ventricular systolic function: a hospital cohort study. Heart. 2005; 91 (7):907–913.
- MacLennan WJ. Diuretics in the elderly: how safe? Br Med J (Clin Res Ed). 1988; 296 (6636):1551–1552.
- Forman DE, Chander RB, Lapane KL et al. Evaluating the use of angiotensin converting enzyme inhibitors for older nursing home residents with chronic heart failure. J Am Geriatr Soc. 1998; 46 (12):1550–1554.