Russian Heart Failure Journal 2008year Heart failure in patients with type 2 diabetes mellitus: problems and solutions


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2008/

Heart failure in patients with type 2 diabetes mellitus: problems and solutions

Atroshchenko E. S.

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Heart failure may be both a consequence and a predisposing factor of type 2 DM. Life prediction for patients with combination of these two comorbidities is extremely unfavorable, especially if CHF was induced by coronary heart disease (CHD). The risk of death due to cardiovascular events in DM is equal to that in CHD, and these two conditions are considered equivalent in this respect. Although a diabetic heart is characterized by LV diastolic dysfunction, risk of coronary death in patients is higher than in individuals with low EF. Treatment of patients with DM and CHD is based on compromises because virtually all antidiabetic drugs exert adverse effects on the myocardium. Drugs of choice include RAAS blockers, metformin and selective β-adrenoblockers.
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