Russian Heart Failure Journal 2008year Gender differences in patients with acute myocardial infarction


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2008/

Gender differences in patients with acute myocardial infarction

Novikova N.A., Gendlin G.E., Storozhakov G.I.

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Article presents a review of data of literature on gender differences in patients with myocardial infarction. It also provides results of an own post hoc study including 217 patients with acute myocardial infarction (AMI), which showed that gender is important for prediction of AMI outcome and that females have worse parameters. Caplan-Meyer survival curves clearly but non-significantly diverged for women in relation to age. The curves for women clearly but also non-significantly diverged starting from the 20 th month in relation to the performed thrombolysis. At the same time, survival curves for all patients and men highly significantly diverged in relation to the performed thrombolysis. The MI localization highly significantly influenced cumulative survival in women. As distinct from many foreign studies, however, authors did not observe any dependence of survival and prediction on the presence of diabetes mellitus and AH in women. The inconsistency with foreign data as well as the insufficient significance of age and thrombolysis effects on IM outcome in women were probably due to the small number of included females.
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