Russian Heart Failure Journal 2007year Study on prevalence and clinical significance of hypotrophy in therapeutic patients (SATURN)
Study on prevalence and clinical significance of hypotrophy in therapeutic patients (SATURN)
Arutyunov A.G., Kostyukevich O.I., Zvonova E.V., Topilskaya N.V.
Many chronic diseases are known to result in progressive loss of body weight. Development of cachexy considerably aggravates the prognosis in patients with somatic pathology. No large studies of undernutrition prevalence in therapeutic patients have been conducted in Russia up to the present. Aim of this study was evaluating the prevalence of undernutrition among patients hospitalized in therapeutic departments or visiting a district physician. Patients were volunteered at hospitals and outpatient clinics in 24 cities of Russia. Patients were enrolled at a random basis, no matter whether they had external signs of undernutrition or not. In overall, 4989 patients (2601 men and 2388 women) aged 56.7±4.3 years were enrolled. Comprehensive evaluation of the nutritive status including measurements of body weight (BW), body weight index (BWI), lean body weight (LBW), laboratory tests, assessment of diet, and correspondence of consumed energy to proper values was performed for all patients. An individual case report was completed for each patient. Study demonstrated a high prevalence of undernutrition among patients visiting a physician; 53.2% of patients had signs of hypotrophy. Of these patients, 61% were patients with CHF, 9.4% – patients with cancer, 9.1% – patients with COLD, 7.4% – patients with hepatic cirrhosis. A dependence of nutritional status on duration of disease and adequacy of drug therapy was revealed in patients with CHF.