Russian Heart Failure Journal 2007year Cardiac septum motions in the region of atrio-ventricular junction in patients with combination of ischemic heart disease and atrial fibrillation
Cardiac septum motions in the region of atrio-ventricular junction in patients with combination of ischemic heart disease and atrial fibrillation
Volkova N. S., Kuznetsova L. I., Parkhanyuk E. V., Shvarts Yu. G.
Urgency. Studies of recent years have considerably expanded the notions on pathophysiological mechanisms of atrial fibrillation (AF). However electrophysiological mechanisms inducing and maintaining AF remain insufficiently studied. Aim. To study myocardial motion in the region of atrio-ventricular junction containing important components of the conduction system in patients with persistent AF (PAF) using tissue Doppler echoCG (Doppler tissue imaging, DTI). Materials and methods. Three groups of patients were evaluated. The first group included 34 patients with IHD and PAF; the second group consisted of 20 patients with IHD and no arrhythmias; the third group consisted of 20 healthy subjects. Doppler echoCG was performed in the DTI mode. Motion of the interatrial septum (IAS) and the interventricular spectum (IVS) were examined. Differences in motion velocities (asynchronism) of the lower IAS and upper IVS were analyzed. Results. It was shown that the asynchronism index in different phases of cardiac cycle was substantially lower in patients with IHD than in healthy subjects. The least difference in motion velocity of adjacent IAS and IVS components was observed in patients with a combination of IHD and PAF. The data confirmed the presence of fibrotic changes in the atrio-ventricular junction revealed by morphological examinations in AF.