Russian Heart Failure Journal 2005year Interrelation between left ventricular diastolic dysfunction and diurnal profile of blood pressure in elderly patient residents of the North
Interrelation between left ventricular diastolic dysfunction and diurnal profile of blood pressure in elderly patient residents of the North
Nuzhnaya T.G., Nuzhnyj V.P., Shmakov D.N., Yastrebova G.N.
Urgency. Changes in diurnal rhythm in elderly may be a result rather than a cause of damage to target organs, specifically the heart. To understand mechanisms of AH development in elderly, it is currently urgent to study the interrelation between parameters of LV diastolic function and various types of BP diurnal curves. Aim of study. Comparing the parameters of functional conditions in LV myocardium with types of BP diurnal curves in elderly. Materials and methods. Sixty patients with I–III degree AH aged from 60 to 73 years and 30 age-matched individuals without apparent disease underwent echoCG and 24-hour BP monitoring. Results. Mean BP diurnal index was abnormal in 65% of patients with AH, with predomination of dippers (21 patients) and non-dippers (27 patients). In control group, mean BP diurnal profile was abnormal in 53.33% of patients with predomination of non-dippers (14 patients). Signs of I type LV diastolic dysfunction were observed in all patients with AH. First type LV diastolic dysfunction was observed in 56.67% (17) of healthy elderly subjects. Results of correlation analysis revealed the presence of a direct relationship between LV diastolic dysfunction and changes in BP diurnal profile in the healthy group (г=0.44).