Russian Heart Failure Journal 2005year Effect of exercise training on structural and geometric and functional LV parameters in elderly patients with II–IV FC CHF (a one-year study)
Effect of exercise training on structural and geometric and functional LV parameters in elderly patients with II–IV FC CHF (a one-year study)
Osipova I.V., Sazanova I.Yu., Berezenko E.A., Efremushkina S.A.
Urgency. Search for new approaches to management of patients with CHF remains a challenging problem of cardiology. In this connection, interest to non-drug treatment, in particular physical rehabilitation for such patients, is growing. Aim. Studying the effect of long-term (up to 12 months) exercise training on LV remodeling processes in elderly patients with II–IV FC CHF. Material and methods. Study enrolled 140 outpatients aged 60-84 years (mean age 67.8±2.1) with II–IV FC CHF. Patients were randomized to 2 groups: group 1 included 70 patients receiving a complex of interval exercise with free choice of exercise parameters (bodily exercise or bicycle exercise) in addition to drug therapy, and group 2 included 70 patients on drug therapy. Left ventricular structural and geometric parameters, LV systolic and diastolic function were evaluated by echoCG at baseline and at 3, 6 and 12 months. Results. In the course of long-term (up to one year) exercise training by the method of free choice of exercise, patients with II–IV FC CHF displayed improvement of structural and geometric and functional LV parameters, which was evident at 6 months and lasted to one year of follow-up. Exercise slowed down the LV remodeling process in patients with IV FC CHF. Drug therapy did not exert any marked effect on myocardial remodeling which have progressed over the entire follow-up period.