Russian Heart Failure Journal 2005year Clinical efficacy of the calcium sensitizer, a representative of a new class of drugs with a positive inotropic effect in heart failure and myocardial infarction


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2005/

Clinical efficacy of the calcium sensitizer, a representative of a new class of drugs with a positive inotropic effect in heart failure and myocardial infarction

Yavelov I.S.

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Article present data on mechanisms of action, pharmacokinetic peculiarities and clinical efficacy of the calcium sensitizer, a representative of a new class of drugs with a positive inotropic effect in heart failure (HF) and myocardial infarction (MI). Current notions of the practical use of levosimendan are based on results of several comparative clinical studies including LIDO, CASINO, and RUSSLAN. Article presents information on safety of levosimendan and discusses possible fields of its application.

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