2017

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2017/№8

Randomized Controlled Trials in Patients With Heart Failure in Russia Following the Study Topcat: What Awaits us in the Future

Lopatin Yu. M.
Volgograd State Medical University; Volgograd Regional Clinical Cardiology Centre, Volgograd, Russia

Keywords:

DOI: 10.18087/cardio.2017.10025

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  2. Pfeffer M.A., Claggett B., Assmann S.F., Boineau R., Anand I.S., Clausell N. et al. Regional variation in patients and outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) trial. Circulation. 2015;131(1): 34–42. doi:10.1161/CIRCULATIONAHA.114.013255.
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  4. de Denus S., O’Meara E., Desai A.S., Claggett B., Lewis E.F., Leclair G. et al. Spironolactone metabolites in TOPCAT – new insights into regional variation. N Engl J Med. 2017;376 (17):1690–2. doi:10.1056/NEJMc1612601.
  5. Ferreira J.P., Girerd N., Rossignol P., Zannad F. Geographic differences in heart failure trials. Eur J Heart Fail. 2015;17(9):893–905. doi:10.1002/ejhf.326.
  6. Ponikowski P., Voors A.A., Anker S.D., Bueno H., Cleland J.G.F., Coats A.J.S. et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur J Heart Fail. 2016 Aug;18(8):891-975. doi: 10.1002/ejhf.592.
  7. Mareev V. Yu., Fomin I. V., Ageev F. T., Arutyunov G. P., Begrambekova Yu. L., Belenkov Yu. N. et al. Clinical guidelines. Chronic heart failure (CHF). Russian Heart Failure Journal. 2017;18 (1):3–40 DOI: 10.18087/rhfj.2017.1.2346.
Lopatin Yu. M. R andomized Controlled Trials in Patients With Heart Failure in Russia Following the Study Topcat: What Awaits us in the Future. Kardiologiia. 2017;57(8):47-50.

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