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Molecular Aspects of Translational Cardiology in Vascular Wall Research

Maksimenko A. V.
Institute of Experimental Cardiology of Russian Cardiology Research and Production Complex, Moscow, Russia

Keywords: endothelial glycocalyx; vascular wall hydration; water-electrolyte exchange; antioxidant enzymes; protein three-dimensional structure modeling

DOI: 10.18087/cardio.2017.7.10008

Clinical-biochemical research of vascular wall hydrated state, water-electrolyte balance has broadened substantially our notions concerning initiation mechanism of vessel damages, methods of their prevention and treatment. Consecutive study of endothelial glycocalyx functioning, computational research of its interaction with oxidative stress, regulation of its state has been aimed at development of novel means of the vascular system protection. Mutual efforts of clinicians and scientists should contribute to the productivity of results of translational cardiology.
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Maksimenko A. V. Molecular Aspects of Translational Cardiology in Vascular Wall Research. Kardiologiia. 2017;57(7):66–79.

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